Sphingomyelin synthase 2 foci assemble at the leading edge of the basal membrane in migrating cells, and these foci eventually become sites of migrasome formation. Conversion of ceramide to sphingomyelin spurs migrasome growth and preserves the structural integrity of these organelles.

中文翻译：

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鞘磷脂合酶 2 焦点决定迁移体形成的位点

鞘磷脂合酶 2 聚集点在迁移细胞的基底膜前缘聚集，这些聚集点最终成为迁移体形成的位点。神经酰胺转化为鞘磷脂可刺激迁移体生长并保持这些细胞器的结构完整性。