Adipokines play a significant role in cardiometabolic diseases. Asprosin, a newly discovered adipokine, was first identified as a glucose-raising protein hormone. Asprosin also stimulates appetite and regulates glucose and lipid metabolism. Its identified receptors so far include Olfr734 and Ptprd. Clinical studies have found that asprosin may be associated with cardiometabolic diseases. Asprosin may have diagnostic and therapeutic potential in obesity, diabetes, metabolic syndrome and atherosclerotic cardiovascular diseases. Herein, the structure, receptors, and functions of asprosin and its relationship with cardiometabolic diseases are summarized based on recent findings.

脂肪因子在心脏代谢疾病中发挥重要作用。白脂素是一种新发现的脂肪因子，最初被鉴定为一种升糖蛋白激素。白脂素还可以刺激食欲并调节葡萄糖和脂质代谢。目前已识别的受体包括 Olfr734 和 Ptprd。临床研究发现白脂素可能与心脏代谢疾病有关。白脂素可能对肥胖、糖尿病、代谢综合征和动脉粥样硬化性心血管疾病具有诊断和治疗潜力。本文根据最新研究成果，总结了白脂素的结构、受体和功能及其与心脏代谢疾病的关系。