An analytical method for nanoplastics with high sensitivity and selectivity is highly desirable to understand the impact of nanoplastics on the environment and human health. In this review article, we outline the challenges in nanoplastics analysis using Raman spectroscopy and provide an overview of the recent progress in nanoplastic analysis by advanced Raman spectroscopy including the hyphenated technology of Raman spectroscopy with other instrumental methods, and surface enhanced Raman spectroscopy (SERS) with conventional SERS substrates and SERS integrated with sample preparation methods, highlighting the efforts made by researchers for improving the sensitivity, spatial resolution, accuracy, precision and feasibility of Raman spectroscopy for nanoplastic analysis. Finally, we summarize the current challenges in nanoplastic analysis by advanced Raman spectroscopy and proposed the opportunities for further research in this field, aiming to fill the knowledge gap and promote the further progress of nanoplastic analysis with advanced Raman spectroscopy.

一种高灵敏度、高选择性的纳米塑料分析方法非常需要了解纳米塑料对环境和人类健康的影响。在这篇综述文章中，我们概述了使用拉曼光谱进行纳米塑料分析的挑战，并概述了先进拉曼光谱在纳米塑料分析方面的最新进展，包括拉曼光谱与其他仪器方法的联用技术，以及表面增强拉曼光谱（SERS）结合传统的SERS基底以及与样品制备方法相结合的SERS，凸显了研究人员为提高拉曼光谱用于纳米塑料分析的灵敏度、空间分辨率、准确性、精密度和可行性所做的努力。最后，