包装用时间温度指示器的原理、研制及应用,Packaging Technology and Science

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包装用时间温度指示器的原理、研制及应用
Packaging Technology and Science ( IF 2.8 ) Pub Date : 2023-06-26 , DOI: 10.1002/pts.2761
Yang Liu ₁ , Lin Li ₁ , Zhumin Yu ₁ , Changqing Ye ₁ , Liao Pan ₂ , Yanlin Song ₃

Affiliation

时间温度指标（TTI）可以直观地反映各种产品的剩余保质期，特别是在冷链运输中，通过考虑时间和温度的影响。尽管已经开发了各种 TTI，但很少有商业化的。本综述旨在为科学界提供及时的参考，并为 TTI 的未来设计以促进商业化提供有价值的指导。本文首先介绍了 TTI 的一般原理和模型，包括反应速率常数、活化能和活化能匹配等关键参数。然后，介绍了四种经典类型的TTI，包括扩散型、聚合物型、酶型和微生物型TTI，介绍了它们的工作机制、优缺点，并以商业化的TTI产品为例。TTI设计和制造的发展趋势从纳米粒子、静电纺纳米纤维和可印刷油墨三大类凸显。此外，该综述还总结了 TTI 在监测各种产品（肉类、海鲜、乳制品、疫苗以及水果和蔬菜）质量和安全方面的最新应用。我们也从安全性、准确性、多功能性和商业化的角度对TTI的未来发展提出了我们的担忧。

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Principle, development and application of time–temperature indicators for packaging

Time–temperature indicators (TTIs) can visually reflect the remaining shelf life of various products, especially in cold chain transportation, by taking consideration of both time and temperature influences. Though various TTIs have been developed, few have been commercialized. This review aims at providing a timely reference to scientific community and valuable guidance for the future design of TTIs to boost the commercialization. This review firstly introduces the general principle and models for TTIs including key parameters of reaction rate constants, activation energies and activation energy matching. Then, four classical types of TTIs covering diffusion-based, polymer-based, enzyme-based, and microbial TTIs are introduced regarding their working mechanisms, advantages and disadvantages as well as commercialized TTI products as examples. The development trend of TTI design and fabrication is highlighted from three categories including nanoparticles, electrospun nanofibers and printable inks. Furthermore, the review summarizes recent application of TTIs for monitoring the quality and safety of various products (meat, seafood, dairy, vaccines and fruits and vegetables). We also point our concerns from the perspective of safety, accuracy, multifunctionality and commercialization for the future development of TTIs.

更新日期：2023-06-26

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