The generation of chirality in supramolecular structures from achiral building blocks has remained a challenge for a long time. In this study, we present a vortex-assisted chiral supramolecular polymerization from a series of achiral C₃-symmetric monomers, where the mechanism of symmetry-breaking is systematically investigated. By increasing the supersaturation, at the early stage of nucleation and growth, highly ordered assemblies can be generated as the initial chiral nuclei. Meanwhile, chiral assemblies from high supersaturation are hard to interwind into clusters, where clusters as nuclei are not conducive to being fractured by sheer force of vortex fluid. Therefore, it is concluded that chiral assemblies in the nucleation stage possess low energy barrier, so that chiral nuclei could be fractured and replicated by the vortex. By enlarging the initial chiral bias, the major chiral nuclei can evolute into the final chiral polymers.

长期以来，从非手性结构单元产生超分子结构的手性一直是一个挑战。在这项研究中，我们提出了一系列非手性 C _{3的涡旋辅助手性超分子聚合}-对称单体，系统地研究了对称性破缺的机制。通过增加过饱和度，在成核和生长的早期阶段，可以生成高度有序的组装体作为初始手性核。同时，高过饱和度形成的手性组装体很难缠绕成团簇，团簇作为核不利于涡流流体的剪切力的作用而破裂。因此，可以得出结论，成核阶段的手性组装体具有低能垒，因此手性核可以被涡流破碎和复制。通过扩大初始手性偏差，主要手性核可以演化成最终的手性聚合物。