Organochlorine pesticides (OCPs) have been used in agriculture, increasing crop yields and representing a serious and persistent global contaminant that is harmful to the environment and human health. OCPs are typically bioaccumulative and persistent chemicals that can spread over long distances. The challenge is to reduce the impacts caused by OCPs, which can be achieved by treating OCPs in an appropriate soil and water environment. Therefore, this report summarizes the process of bioremediation with commercially available OCPs, considering their types, impacts, and characteristics in soil and water sources. The methods explained in this report were considered to be an effective and environmentally friendly technique because they result in the complete transformation of OCPs into a non-toxic end product. This report suggests that the bioremediation process can overcome the challenges and limitations of physical and chemical treatment for OCP removal. Advanced methods such as biosurfactants and genetically modified strains can be used to promote bioremediation of OCPs.