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Reactions of phenol and its derivatives with levoglucosenone
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2023-06-29 , DOI: 10.1007/s10593-023-03190-2
Liliya Kh. Faizullina , Liliya Sh. Karamysheva , Yuliya A. Khalilova , Shamil M. Salikhov , Farid A. Valeev

The effect of hydroxy-, methyl-, and benzyloxy substituents in the corresponding phenol derivatives on the result of the Michael addition to levoglucosenone in the presence of AlCl3 or FeCl3 was studied. The reaction of phenols containing hydroxyl and methyl groups in the ortho position with levoglucosenone concludes with spontaneous ketalization of the carbohydrate keto group. The obtained compounds are promising in terms of studying their structure–activity relationship.



中文翻译:

苯酚及其衍生物与左旋葡萄糖烯酮的反应

研究了在AlCl 3或FeCl 3存在下相应苯酚衍生物中的羟基、甲基和苄氧基取代基对左旋葡萄糖烯酮迈克尔加成结果的影响。位含有羟基和甲基的酚与左旋葡萄糖烯酮的反应以碳水化合物酮基的自发缩酮化结束。所获得的化合物在研究其结构-活性关系方面具有广阔的前景。

更新日期:2023-06-30
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