Historical Records of Australian Science ( IF 0.2 ) Pub Date : 2023-06-22 , DOI: 10.1071/hr23004 Racheline (Lynn) Rogers
George Rogers (1927–2021) was elected to Fellowship of the Academy in 1977 for his outstanding contributions to our knowledge of the molecular structure of keratins and the biochemistry of keratinisation. He was a pioneer in the application of electron microscopy to hair and wool ultrastructure and to that of the hair follicle. He discovered citrulline in keratin proteins, and the enzymes, roles, and histochemical localisation of transglutaminase and peptidylarginine deiminase (PAD). He was the first to demonstrate ribosomal-dependent keratin protein synthesis in 1965 followed by detailed studies of the biosynthesis of hair keratin proteins. His research initiated studies on the molecular events in the development of the feather follicle and later led to the cloning and characterisation of the clustered genes of feather and related avian keratins. He also cloned and characterised genes for the three classes of wool keratin proteins and studied the transcription of keratin genes. In 1977, he was awarded a DSc by the University of Adelaide in recognition for his work. In 2013, he was made an Officer in the Order of Australia.
中文翻译:
乔治·欧内斯特·罗杰斯 1927–2021
乔治·罗杰斯(George Rogers,1927-2021)因其对角蛋白分子结构和角化生物化学知识的杰出贡献而于 1977 年当选为学院院士。他是将电子显微镜应用于头发和羊毛超微结构以及毛囊超微结构的先驱。他发现了角蛋白中的瓜氨酸,以及转谷氨酰胺酶和肽基精氨酸脱亚胺酶 (PAD) 的酶、作用和组织化学定位。1965 年,他第一个证明了核糖体依赖性角蛋白的合成,随后对头发角蛋白的生物合成进行了详细研究。他的研究启动了对羽毛毛囊发育中分子事件的研究,后来导致了羽毛和相关鸟类角蛋白的簇基因的克隆和表征。他还克隆并鉴定了三类羊毛角蛋白的基因,并研究了角蛋白基因的转录。1977年,阿德莱德大学授予他理学硕士学位,以表彰他的工作。2013年,他被授予澳大利亚军官勋章。