With the trend of sustainable development and the complex medical environment, there is a strong demand for multimodal antibacterial cellulose wound dressing (MACD) with photothermal therapy (PTT). Herein, a novel MACD fabrication strategy with PTT was proposed and implemented through graft polymerization of an imidazolium ionic liquid monomer containing iron complex anion structure. The fabricated hydrogels exhibited excellent antibacterial properties because of the efficient photothermal conversion ability (68.67 %) of ionic liquids and the intrinsic structural characteristic of quaternary ammonium salts. The antibacterial ratio of cellulosic hydrogel dressings to S. aureus and E. coli could reach 99.57 % and 99.16 %, respectively. Additionally, the fabricated hydrogels demonstrated extremely low hemolysis rates (<5 %) and excellent cell viability (~>85 %). Furthermore, in vivo antibacterial experimental results proved that the fabricated antibacterial dressings could significantly accelerate wound healing. Therefore, the proposed strategy would provide a new method of designing and preparing high-performance cellulose wound dressings.

随着可持续发展的趋势和复杂的医疗环境，对光热疗法（PTT）多模式抗菌纤维素伤口敷料（MACD）有强烈的需求。在此，提出并通过含有铁络合物阴离子结构的咪唑鎓离子液体单体的接枝聚合实现了一种新型的PTT MACD 制造策略。由于离子液体高效的光热转换能力（68.67%）和季铵盐的固有结构特征，所制备的水凝胶表现出优异的抗菌性能。纤维素水凝胶敷料对金黄色葡萄球菌和大肠杆菌的抗菌率分别可达99.57%和99.16%。此外，制备的水凝胶表现出极低的溶血率（<5%）和优异的细胞活力（~>85%）。此外，体内抗菌实验结果证明，所制备的抗菌敷料可以显着加速伤口愈合。因此，所提出的策略将为设计和制备高性能纤维素伤口敷料提供一种新方法。