Rheological analysis is an important tool to investigate the structural characteristics of materials widely used in the biomedical field, such as polymer solutions, colloids, and hydrogels. In this work, we studied the rheological properties of a colloidal system composed of carboxymethyl cellulose (CMC) and Laponite, both biocompatible materials. Rheological properties of CMC/Laponite aqueous dispersions are influenced by electrostatic interactions and hydrogen bonds between the silanol (Si–O) groups of Laponite and hydroxyl (-OH) of CMC. It was found that the effect of Laponite rheological behavior is strongly affected by CMC concentration, resulting in weak or strong gels. Adding CMC reinforces the blended network, increasing the storage \(\left({G}^{^{\prime}}\right)\) and loss \(\left(G''\right)\) moduli, as well as viscosity. CMC/Laponite gels presented strong shear-thinning and thixotropy due to structural rearrangements when subjected to shear stresses. Moreover, time sweep tests revealed that adding CMC inhibited Laponite aging.

Graphical Abstract

中文翻译：

---

羧甲基纤维素溶液对合成锂皂石分散体流变性能的影响

流变分析是研究生物医学领域广泛使用的材料（例如聚合物溶液、胶体和水凝胶）结构特征的重要工具。在这项工作中，我们研究了由羧甲基纤维素 (CMC) 和锂皂石（这两种生物相容性材料）组成的胶体系统的流变特性。CMC/Laponite 水分散体的流变特性受到 Laponite 的硅烷醇 (Si-O) 基团与 CMC 的羟基 (-OH) 之间的静电相互作用和氢键的影响。研究发现，Laponite 流变行为的效果受到 CMC 浓度的强烈影响，导致凝胶强度变弱或变强。添加 CMC 增强了混合网络，增加了存储\(\left({G}^{^{\prime}}\right)\)和损失\(\left(G''\right)\)模量以及粘度。CMC/Laponite 凝胶在受到剪切应力时由于结构重排而表现出强烈的剪切稀化和触变性。此外，时间扫描测试表明，添加 CMC 可以抑制合成锂皂石的老化。

图形概要