Polymeric STING Pro-agonists for Tumor-Specific Sonodynamic Immunotherapy,Angewandte Chemie International Edition

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Polymeric STING Pro-agonists for Tumor-Specific Sonodynamic Immunotherapy
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2023-06-13 , DOI: 10.1002/anie.202307272
Jie Yu ₁ , Shasha He ₁ , Chi Zhang ₁ , Cheng Xu ₁ , Jingsheng Huang ₁ , Mengke Xu ₁ , Kanyi Pu _{1,

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Affiliation

Polymeric STING pro-agonists (PSPA), whose sono-immunotherapeutic efficacy is activated by sono-irradiation and elevated glutathione (GSH) within the tumor microenvironment (TME), were developed for precision cancer immunotherapy with minimized side effects.

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