Blue LED Induced Three Component Reactions for the Generation of 4,6-Dioxo-hexahydro-1H-furo[3, 4-c] pyrrole: Their Evaluation as Anticancer Agents through PARP-1 Inhibition,Chemistry - An Asian Journal

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Blue LED Induced Three Component Reactions for the Generation of 4,6-Dioxo-hexahydro-1H-furo[3, 4-c] pyrrole: Their Evaluation as Anticancer Agents through PARP-1 Inhibition
Chemistry - An Asian Journal ( IF 3.5 ) Pub Date : 2023-06-12 , DOI: 10.1002/asia.202300420
Haya Khan ₁ , Souvik Guha ₁ , Mousumi Baruah ₁ , Shalini Yadav ₁ , Sanjana Maheshwari ₁ , Sara Sainani ₁ , Debajit Maiti ₁ , Subhabrata Sen ₁

Affiliation

Blue LED induced carbonyl ylide formation, their 1, 3-cycloaddition to a generate 4, 6-dioxo-hexahydro-1H-furo[3, 4-c] pyrroles as potential PARP inhibitors.

中文翻译：

蓝色 LED 诱导产生 4,6-二氧代-六氢-1H-呋喃[3, 4-c]吡咯的三组分反应：通过抑制 PARP-1 对其作为抗癌剂进行评估

蓝色 LED诱导羰基叶立德形成，它们通过 1, 3-环加成生成 4, 6-二氧代-六氢-1H-呋喃[3, 4-c]吡咯，作为潜在的 PARP 抑制剂。

更新日期：2023-06-12

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