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Oyez, Oyez, Oyez!
Nature Immunology ( IF 27.7 ) Pub Date : 2023-06-12 , DOI: 10.1038/s41590-023-01541-x
Philippa M Saunders 1 , Andrew G Brooks 1 , Jamie Rossjohn 2, 3
Affiliation  

Presentation of signal peptides by HLA-E to natural killer cells prevents cell lysis via interactions with the inhibitory CD94–NKG2A receptor. A study now reveals an unexpected level of sophistication and heterogeneity in this receptor–ligand interaction.

中文翻译:

奥耶兹,奥耶兹,奥耶兹!

HLA-E 向自然杀伤细胞呈递信号肽,通过与抑制性 CD94–NKG2A 受体相互作用来防止细胞裂解。现在的一项研究揭示了这种受体-配体相互作用的复杂性和异质性达到了意想不到的程度。
更新日期:2023-06-13
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