We investigated the relationships of the arcuate fasciculus (AF) and the nigrostriatal tract (NST) with the language ability in patients with putaminal hemorrhage (PH) in the dominant hemisphere, using diffusion tensor tractography (DTT). Twenty-seven consecutive right-handed patients with PH and 27 age- and sex-matched normal control subjects were recruited. The aphasia quotient (AQ) score was used to evaluate the language ability at the early stage (within six weeks after onset). The fractional anisotropy (FA) value and tract volume (TV) of the ipsilesional AF and the ipsilesional NST were measured. The FA values and TVs of the ipsilesional AF and the ipsilesional NST of the patient group were lower than those of the control group (p < 0.05). The AQ score showed no significant correlation with the FA values of the ipsilesional AF and the ipsilesional NST (p > 0.05). By contrast, the AQ score showed a strong positive correlation with the TV of the ipsilesional AF (r = 0.868, p < 0.05). In addition, the AQ score revealed a moderate positive correlation with the TV of the ipsilesional NST (r = 0.577, p < 0.05). The states of the ipsilesional AF and the ipsilesional NST were closely related to the language ability at the early stages in patients with PH in the dominant hemisphere. Furthermore, the ipsilesional AF was more closely related to the language ability than the ipsilesional NST.

我们使用弥散张量纤维束成像 (DTT) 研究了弓状束 (AF) 和黑质纹状体束 (NST) 与优势半球壳核出血 (PH) 患者语言能力的关系。招募了 27 名连续的右利手 PH 患者和 27 名年龄和性别匹配的正常对照受试者。失语商数（AQ）评分用于评估早期（发病后六周内）的语言能力。测量同侧 AF 和同侧 NST 的分数各向异性 (FA) 值和束容积 (TV)。患者组同侧 AF 和同侧 NST 的 FA 值和 TVs 均低于对照组（p < 0.05)。AQ 评分与同侧 AF 和同侧 NST 的 FA 值无显着相关性 ( p  > 0.05)。相比之下，AQ 评分与同侧 AF 的 TV 呈强正相关（r  = 0.868，p  < 0.05）。此外，AQ 评分显示与同侧 NST 的 TV 呈中度正相关（r  = 0.577，p  < 0.05）。同侧AF和同侧NST的状态与优势半球PH患者早期的语言能力密切相关。此外，同侧 AF 与语言能力的关系比同侧 NST 更密切。