A novel three-component Pd/norbornene cooperative catalysis cascade decarboxylative [2+2+2]/[2+2+3]cyclization of 4-iodoisoquinolin-1(2H)-ones and o-bromobenzoic acids or 8-bromo-1-naphthoic acid has been developed. The method affords a range of fused phenanthridinones and hepta[1,2-c]isoquinolinones and displays unique regioselectivity and broad substrate scope. Palladium/norbornene (Pd/NBE)-catalyzed C–H activation and subsequent decarboxylative coupling reactions were involved, and NBE acts as a building block for the construction of rigid nonplanar molecular architectures.

中文翻译：

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钯/降冰片烯协同催化 4-碘异喹啉-1(2H)-酮与邻溴苯甲酸的级联脱羧环化：获得多种稠合菲啶酮和七[1,2-c]异喹啉酮

4-碘异喹啉-1(2 H)-酮与邻溴苯甲酸或8-溴-的新型三组分Pd/降冰片烯协同催化级联脱羧[2+2+2]/[2+2+ 3 ]环化已开发出1-萘甲酸。该方法提供了一系列稠合菲啶酮和七[1,2- c ]异喹啉酮，并显示出独特的区域选择性和广泛的底物范围。钯/降冰片烯 (Pd/NBE) 催化的 C-H 活化和随后的脱羧偶联反应参与其中，NBE 充当构建刚性非平面分子结构的构建块。