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Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade**
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2023-05-26 , DOI: 10.1002/chem.202301503
Michael K F Mohr 1 , Raspudin Saleem-Batcha 1 , Nicolas V Cornelissen 2 , Jennifer N Andexer 1
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2023-05-26 , DOI: 10.1002/chem.202301503
Michael K F Mohr 1 , Raspudin Saleem-Batcha 1 , Nicolas V Cornelissen 2 , Jennifer N Andexer 1
Affiliation
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O-acetyl-l-homoserine sulfhydrolase is used for the production of l-methionine analogues from l-homocysteine and off-the shelf organic thiols. Combined with methyltransferase-catalysed alkylation cascades, this enables the transfer of a wide range of moieties onto various substrates.
中文翻译:
L-蛋氨酸类似物的酶法合成及其在甲基转移酶催化烷基化级联中的应用**
O-乙酰基-L-高丝氨酸磺基水解酶用于从L-高半胱氨酸和现成的有机硫醇生产L-甲硫氨酸类似物。与甲基转移酶催化的烷基化级联相结合,这使得多种基团能够转移到各种底物上。
更新日期:2023-05-26
中文翻译:

L-蛋氨酸类似物的酶法合成及其在甲基转移酶催化烷基化级联中的应用**
O-乙酰基-L-高丝氨酸磺基水解酶用于从L-高半胱氨酸和现成的有机硫醇生产L-甲硫氨酸类似物。与甲基转移酶催化的烷基化级联相结合,这使得多种基团能够转移到各种底物上。