Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade**,Chemistry - A European Journal

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Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade**
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2023-05-26 , DOI: 10.1002/chem.202301503
Michael K F Mohr ₁ , Raspudin Saleem-Batcha ₁ , Nicolas V Cornelissen ₂ , Jennifer N Andexer ₁

Affiliation

O-acetyl-l-homoserine sulfhydrolase is used for the production of l-methionine analogues from l-homocysteine and off-the shelf organic thiols. Combined with methyltransferase-catalysed alkylation cascades, this enables the transfer of a wide range of moieties onto various substrates.

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