An efficient synthesis of 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one derivatives and investigation as potential anticancer agents are reported. Characterization of the obtained compounds is established utilizing IR,¹³C NMR, ¹H NMR, and single crystal X-ray. In vitro anticancer effects of compounds are evaluated by MTT assay. Findings reveal that some compounds can be of significance as anticancer drug candidates for future research.

中文翻译：

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4-Amino-3-Mercapto-6-Methyl-1,2,4-Triazin-5(4H)-One 衍生物的合成、反应性和抗癌活性评价

报道了 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4 H )-one 衍生物的有效合成以及作为潜在抗癌剂的研究。^{利用 IR、 13} C NMR、¹ H NMR 和单晶 X 射线确定所获得化合物的表征。通过MTT法评价化合物的体外抗癌作用。研究结果表明，某些化合物可能作为未来研究的抗癌候选药物具有重要意义。