Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels–Alder reaction,Chemical Communications

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Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels–Alder reaction
Chemical Communications ( IF 4.3 ) Pub Date : 2023-05-16 , DOI: 10.1039/d3cc01641b
Yu-Hang Miao ₁ , Yuan-Zhao Hua ₁ , Shi-Kun Jia ₁ , Xiao Xiao ₂ , Min-Can Wang ₁ , Guang-Jian Mei ₁

Affiliation

The first Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels–Alder reaction has been accomplished. This protocol was carried out by a dual-activation mode under mild conditions, allowing the preparation of various biologically important dihydropyrans in good yields with excellent stereoselectivities.

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