In this study, a spray-drying approach is presented to develop (1) Cu-based metal–organic framework (Cu-MOF) supported on aluminum oxide nanoparticle cluster and (2) its derived Cu-ZnO/Al₂O₃ hybrid catalyst for combined (CO + CO₂) hydrogenation to methanol. The results show superior high space time yield, 23.14 mmol gcat^-1h⁻¹, and selectivity to methanol (85%) were achievable under a moderate-pressure (30 bar) and relatively low-temperature (220 °C) operation. Incorporation of ZnO and Al₂O₃ (i.e., in the form of nanoparticle cluster) enhanced the dispersion and the redox ability of Cu in the MOF-derived catalyst, both of which were critical factors to the catalytic activity toward the combined hydrogenation of CO₂ and CO to methanol. An optimal performance, in terms of the methanol yield, was achieved by using the catalyst with a Cu/Zn molar ratio of 2 and partially reduction by H₂ at a relatively lower temperature (300 °C). The work demonstrates a new route for the design of MOF-derived catalyst by using an aerosol-assisted synthesis approach, showing promise for the catalysis of a variety of chemical reactions in the field of CO₂ capture and utilization.

在这项研究中，提出了一种喷雾干燥方法来开发 (1) 负载在氧化铝纳米粒子簇上的铜基金属有机骨架 (Cu-MOF) 和 (2) 其衍生的 Cu-ZnO/Al 2  O ₃杂_化催化剂联合 (CO + CO ₂ ) 加氢生成甲醇。结果表明，在中等压力 (30 bar) 和相对低温 (220 °C) 的操作下，可实现出色的高时空产率 23.14 mmol gcat ^-1 h ^{-1和对甲醇的选择性 (85%)。}ZnO和Al ₂ O _3的掺入（即以纳米粒子簇的形式）增强了 Cu 在 MOF 衍生催化剂中的分散性和氧化还原能力，这两者都是对 CO 2 和 CO 联合加氢制甲醇的催化活性的关键_因素。通过使用 Cu/Zn 摩尔比为 2 的催化剂并在相对较低的温度 (300 °C) 下通过 H ₂进行部分还原，实现了就甲醇产率而言的最佳性能。_{该工作展示了一种使用气溶胶辅助合成方法设计 MOF 衍生催化剂的新路线，有望在 CO 2}捕获和利用领域催化多种化学反应。