The PbO₂-based electrocatalysts were synthesized on antimony-doped tin oxide (ATO)/Ti substrate by anodic electrodeposition for oxygen evolution reaction (OER) in acidic media. Different additives, such as fluorine, iron, and cobalt ions, were used to modify the PbO₂ performance for enhancement within the electrocatalytic stability and activity. The water contact angle (WCA) measurements showed that after activating the electrodes, the angles ranged from 8° to 12.5° (depending on the dopants type and amount). Fe and Co doping in the electrode led to a reduction of the anodic Tafel constant from 253 for PbO₂-F to 198 and 207 mV.dec⁻¹, respectively. Also, PbO₂-F-Fe-Co exhibited the lowest overpotential at 10 mA.cm⁻² (η₁₀ = 0.307 V), which was incredibly reduced compared to the PbO₂-F electrode (η₁₀ = 0.637 V). An accelerated lifetime test (ALT) at an applied current density of 2.5 A.cm⁻² reported an increase of 161 h (ca. four times) in the life of the F, Co, and Fe tri-doped lead dioxide compared to the undoped one. In addition, X-ray diffraction (XRD) along with microscopic, and electrochemical analyzes were performed after 10,000 voltammetric cycles to comprehend the deactivation mechanisms of the PbO₂-F-Fe-Co electrode which was the most stable among all deposited electrodes. The results demonstrated that the PbO₂-F-Fe-Co electrocatalyst can be a highly efficient and durable alternative to noble metal-based electrocatalysts in OER and provided valuable insights into effective and sustainable electrocatalysts.