Design of a Bilateral Disulfurating Reagent for Unsymmetrical Polysulfidation,Angewandte Chemie International Edition

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Design of a Bilateral Disulfurating Reagent for Unsymmetrical Polysulfidation
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2023-04-21 , DOI: 10.1002/anie.202302861
Qingqiang Tian ₁ , Yahui Li ₁

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A bilateral disulfurating reagent is designed, allowing diverse functional groups to be bridged via S−S bonds. With this reagent, diverse electrophiles including inactivated alkyl Cl/Br/I/OMs and benzyl chloride, natural products, agrochemicals, and pharmaceuticals can be successively cross-linked with S−S bonds. Some products of this work showed good antibacterial activities.

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