AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin,International Journal of Developmental Neuroscience

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AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin
International Journal of Developmental Neuroscience ( IF 1.7 ) Pub Date : 2023-04-20 , DOI: 10.1002/jdn.10261
Ziling Cai ₁ , Zihao Shen ₁ , Jing Zhao ₂ , Hao Zhang ₁ , Zhen Guo ₁ , Qingqian Xia ₁ , Hang Liang ₁ , Junnan Liu ₁ , Lihao Tan ₁ , Huajun Sheng ₁ , Shujuan Zhu ₁

Affiliation

The purpose of this work is to examine the impact of AQP8 on the proliferation and development of human glioma cell lines A172 and U251 and to determine if aquaporin 8 (AQP8) is associated with GSK-3β phosphorylation and nuclear transport of β-catenin in the Wnt signaling pathway.

中文翻译：

AQP8可能通过调节β-连环蛋白的GSK-3β磷酸化和核转运来影响神经胶质瘤的增殖和生长

这项工作的目的是检查 AQP8 对人神经胶质瘤细胞系 A172 和 U251 增殖和发育的影响，并确定水通道蛋白 8 (AQP8) 是否与 GSK-3β 磷酸化和 β-连环蛋白的核转运相关。 Wnt信号通路。

更新日期：2023-04-20

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