Multiprincipal-element alloys are an enabling class of materials owing to their impressive mechanical and oxidation-resistant properties, especially in extreme environments^1,2. Here we develop a new oxide-dispersion-strengthened NiCoCr-based alloy using a model-driven alloy design approach and laser-based additive manufacturing. This oxide-dispersion-strengthened alloy, called GRX-810, uses laser powder bed fusion to disperse nanoscale Y₂O₃ particles throughout the microstructure without the use of resource-intensive processing steps such as mechanical or in situ alloying^3,4. We show the successful incorporation and dispersion of nanoscale oxides throughout the GRX-810 build volume via high-resolution characterization of its microstructure. The mechanical results of GRX-810 show a twofold improvement in strength, over 1,000-fold better creep performance and twofold improvement in oxidation resistance compared with the traditional polycrystalline wrought Ni-based alloys used extensively in additive manufacturing at 1,093 °C^5,6. The success of this alloy highlights how model-driven alloy designs can provide superior compositions using far fewer resources compared with the ‘trial-and-error’ methods of the past. These results showcase how future alloy development that leverages dispersion strengthening combined with additive manufacturing processing can accelerate the discovery of revolutionary materials.

多主元合金因其令人印象深刻的机械和抗氧化性能而成为一类可行的材料，特别是在极端环境中^1,2 。在这里，我们使用模型驱动的合金设计方法和基于激光的增材制造开发了一种新型氧化物弥散强化的 NiCoCr 基合金。这种氧化物弥散强化合金称为 GRX-810，它使用激光粉末床熔合将纳米级 Y ₂ O ₃颗粒分散到整个微观结构中，而无需使用机械或原位合金化等资源密集型加工步骤^3,4 。我们通过对其微观结构的高分辨率表征，展示了纳米级氧化物在整个 GRX-810 构建体积中的成功掺入和分散。与在 1,093 °C 增材制造中广泛使用的传统多晶变形镍基合金相比，GRX-810 的机械结果显示强度提高了一倍，蠕变性能提高了 1,000 多倍，抗氧化性提高了两倍^5,6 。这种合金的成功凸显了模型驱动的合金设计如何使用比过去的“试错”方法少得多的资源提供优异的成分。这些结果展示了利用弥散强化与增材制造工艺相结合的未来合金开发如何能够加速革命性材料的发现。