Synthesis of 2-substituted bicyclo[1.1.0]butanes via zincocyclopropanation using bromoform as the carbenoid precursor,Chemical Communications

当前位置： X-MOL 学术 › Chem. Commun. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Synthesis of 2-substituted bicyclo[1.1.0]butanes via zincocyclopropanation using bromoform as the carbenoid precursor
Chemical Communications ( IF 4.3 ) Pub Date : 2023-04-14 , DOI: 10.1039/d3cc00335c
Léa Thai-Savard ₁ , André B Charette ₁

Affiliation

Through a revisited Simmons–Smith type zincocyclopropanation using bromoform as the carbenoid source, the synthesis of 2-, 2,2- and 2,4-substituted bicyclo[1.1.0]butanes is reported. Few antecedents of the derivatives have yet been described. Ultimately, the underexplored scaffolds exhibited a complete discrepency of reactivity.

中文翻译：

以溴仿为类胡萝卜素前体通过锌基环丙烷化反应合成 2-取代双环[1.1.0]丁烷

通过使用三溴甲烷作为类胡萝卜素来源重新审视的 Simmons-Smith 型锌基环丙烷化反应，报道了 2-、2,2- 和 2,4- 取代的双环[1.1.0] 丁烷的合成。几乎没有描述衍生物的前因。最终，未充分探索的支架表现出完全不同的反应性。

更新日期：2023-04-14

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南