The manuscript proposes a novel dielectrically modulated Non-Uniform Tunnel FET based Biosensor for the detection of charged and neutral biomolecules. In this work, the reliability analysis of Dual Material Source based Non-Uniform Tunnel FET Biosensor has been performed. The design of Non-Uniform Tunnel FET and doping profile at the tunneling junction is accountable for the improved sensitivity. The response of the proposed biosensor has been analysed in terms of threshold voltage sensitivity, ON-OFF current ratio sensitivity and drain current sensitivity by using Sentaurus TCAD device simulator. The investigation includes analysis of neutral, positive and negatively charged Bio-analytes at immobilization layer for different cases of dielectrics. In case of positively charged Bio-analytes, it has been observed that the proposed biosensor can obtain the highest sensitivities of 100 mV, 7.9 × 10⁶, 451 for threshold voltage, ON-OFF current ratio, and drain current sensitivities, respectively. Furthermore, the performance and reliability assessment of the biosensor have been considered using the appearance of steric hindrance in different patterns and temperature fluctuations in the wide range from 200 K to 400 K.

该手稿提出了一种基于介电调制的非均匀隧道 FET 的新型生物传感器，用于检测带电和中性生物分子。在这项工作中，对基于双材料源的非均匀隧道 FET 生物传感器进行了可靠性分析。非均匀隧道 FET 的设计和隧道结处的掺杂分布是提高灵敏度的原因。通过使用 Sentaurus TCAD 器件模拟器，已根据阈值电压灵敏度、ON-OFF 电流比灵敏度和漏极电流灵敏度分析了所提出的生物传感器的响应。该调查包括针对不同电介质情况在固定层分析中性、带正电和带负电的生物分析物。对于带正电的生物分析物，^在图6中，451分别表示阈值电压、ON-OFF电流比和漏电流灵敏度。此外，生物传感器的性能和可靠性评估已被考虑使用不同模式的空间位阻外观和 200 K 至 400 K 的宽范围内的温度波动。