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Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis
World Journal of Emergency Surgery ( IF 6.0 ) Pub Date : 2023-03-29 , DOI: 10.1186/s13017-023-00492-w
Mingxuan Li 1 , Yu Yan 1 , Chaonan Wang 2 , Haixia Tu 1
Affiliation  

Studies on the mortality of blunt abdominal aortic injury (BAAI) are rare and have yielded inconsistent results. In the present study, we aimed to quantitatively analyse the retrieved data to more accurately determine the hospital mortality of BAAI. The Excerpta Medica Database, PubMed, Web of Science and Cochrane Library databases were searched to identify relevant publications without date restrictions. The overall hospital mortality (OHM) of BAAI patients was set as the primary outcome measure. English publications with data that met the selection criteria were included. The quality of all included studies was assessed by the Joanna Briggs Institute checklist and the American Agency for Health Care Quality and Research’s cross-sectional study quality evaluation items. After data extraction, a meta-analysis of the Freeman–Tukey double arcsine transformation of data was performed using the Metaprop command in Stata 16 software. Heterogeneity was assessed and reported as a percentage using the I2 index value and as a P value using the Cochrane Q test. Various methods were used to determine the sources of heterogeneity and to analyse the sensitivity of the computation model. Of the 2147 references screened, 5 studies that involved 1593 patients met the selection criteria and were included. There were no low-quality references after assessment. One study that only included 16 juvenile BAAI patients was excluded from the meta-analysis of the primary outcome measure due to high heterogeneity. Due to the low heterogeneity (I2 = 47.6%, P = 0.126 for Q test) that was observed after using the random effects model, the fixed model was subsequently used to pool the effect sizes of the remaining four studies, thus yielding an OHM of 28.8% [95% confidence interval (CI) 26.5–31.1%]. The stability of the model was verified by sensitivity analysis, and Egger’s test (P = 0.339) indicated a low level of publication bias. In addition, we also performed meta-analyses and obtained a pooled hospital mortality of operation (13.5%, 95% CI 8.0–20.0%), a pooled hospital mortality of non-operation (28.4%, 95% CI 25.9–31.0%), and a pooled rate of aortic rupture (12.2%, 95% CI 7.0–18.5%) of BAAI. The present study indicated that BAAI has an OHM of 28.8%, indicating that this disease deserves more attention and research.

中文翻译:

钝性腹主动脉损伤 (BAAI) 的医院死亡率:系统评价和荟萃分析

关于钝性腹主动脉损伤 (BAAI) 死亡率的研究很少,而且得出的结果也不一致。在本研究中,我们旨在定量分析检索到的数据,以更准确地确定 BAAI 的院内死亡率。搜索了 Excerpta Medica 数据库、PubMed、Web of Science 和 Cochrane Library 数据库,以确定没有日期限制的相关出版物。BAAI 患者的总体医院死亡率 (OHM) 被设定为主要结果指标。包含符合选择标准的数据的英文出版物。所有纳入研究的质量均由乔安娜布里格斯研究所清单和美国卫生保健质量与研究机构的横断面研究质量评估项目进行评估。数据提取后,使用 Stata 16 软件中的 Metaprop 命令对数据的 Freeman-Tukey 双反正弦变换进行元分析。使用 I2 指数值评估异质性并报告为百分比,并使用 Cochrane Q 检验报告为 P 值。各种方法被用来确定异质性的来源和分析计算模型的敏感性。在筛选的 2147 篇参考文献中,涉及 1593 名患者的 5 项研究符合选择标准并被纳入。评估后没有低质量的参考文献。一项仅包括 16 名少年 BAAI 患者的研究由于高度异质性而被排除在主要结果测量的荟萃分析之外。由于使用随机效应模型后观察到的异质性较低(I2 = 47.6%,Q 检验 P = 0.126),固定模型随后用于合并其余四项研究的效应量,从而产生 OHM 为 28.8% [95% 置信区间 (CI) 26.5–31.1%]。通过敏感性分析验证了模型的稳定性,Egger 检验 (P = 0.339) 表明存在低水平的发表偏倚。此外,我们还进行了荟萃分析并获得了手术合并住院死亡率(13.5%,95% CI 8.0-20.0%),非手术合并住院死亡率(28.4%,95% CI 25.9-31.0%) , 和 BAAI 的主动脉破裂合并率 (12.2%, 95% CI 7.0–18.5%)。目前的研究表明,BAAI 的 OHM 为 28.8%,表明该疾病值得更多关注和研究。通过敏感性分析验证了模型的稳定性,Egger 检验 (P = 0.339) 表明存在低水平的发表偏倚。此外,我们还进行了荟萃分析并获得了手术合并住院死亡率(13.5%,95% CI 8.0-20.0%),非手术合并住院死亡率(28.4%,95% CI 25.9-31.0%) , 和 BAAI 的主动脉破裂合并率 (12.2%, 95% CI 7.0–18.5%)。目前的研究表明,BAAI 的 OHM 为 28.8%,表明该疾病值得更多关注和研究。通过敏感性分析验证了模型的稳定性,Egger 检验 (P = 0.339) 表明存在低水平的发表偏倚。此外,我们还进行了荟萃分析并获得了手术合并住院死亡率(13.5%,95% CI 8.0-20.0%),非手术合并住院死亡率(28.4%,95% CI 25.9-31.0%) , 和 BAAI 的主动脉破裂合并率 (12.2%, 95% CI 7.0–18.5%)。目前的研究表明,BAAI 的 OHM 为 28.8%,表明该疾病值得更多关注和研究。和 BAAI 的合并主动脉破裂率 (12.2%, 95% CI 7.0–18.5%)。目前的研究表明,BAAI 的 OHM 为 28.8%,表明该疾病值得更多关注和研究。和 BAAI 的合并主动脉破裂率 (12.2%, 95% CI 7.0–18.5%)。目前的研究表明,BAAI 的 OHM 为 28.8%,表明该疾病值得更多关注和研究。
更新日期:2023-03-30
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