An Intelligent Laser-Free Photodynamic Therapy Based on Endogenous miRNA-Amplified CRET Nanoplatform**,Chemistry - A European Journal

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An Intelligent Laser-Free Photodynamic Therapy Based on Endogenous miRNA-Amplified CRET Nanoplatform**
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2023-03-29 , DOI: 10.1002/chem.202300861
Benrui Weng ₁ , Yifei Wang ₂ , Siyuan Wang ₁ , Yaqi Liu ₁ , Nana Kang ₁ , Sijia Liu ₁ , Jiabing Ran ₁ , Zhangshuang Deng ₁ , Changying Yang ₁ , Decheng Wang ₃ , Huimin Wang ₁ , Fuan Wang ₂

Affiliation

Tumor biomarker-responsive theranostic holds great promise for precise medicine. Herein, a miRNA-amplified chemiluminescence resonance energy transfer (CRET) nanoplatform was constructed for tumor-specific laser-free photodynamic therapy. It exhibited prominent on-demand in vivo tumor inhibition effects, indicating an intelligent medicine.

中文翻译：

基于内源性 miRNA 扩增 CRET 纳米平台的智能无激光光动力疗法**

肿瘤生物标志物响应治疗诊断学为精准医学带来了巨大希望。在此，构建了 miRNA 放大的化学发光共振能量转移 (CRET) 纳米平台，用于肿瘤特异性无激光光动力疗法。它在体内表现出显着的按需抑瘤效果，是一种智能药物。

更新日期：2023-03-29

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