This study investigated the effects of adenosine (ADO) and adenosine 5′-monophosphate (AMP) supplementation on the growth performance, carcass characteristics, meat quality, and lipid metabolism in adipose tissues of finishing pigs. The pigs were allocated to three treatment groups: the control diet, 0.2%ADO diet, or 0.2%AMP diet. Compared with CON group (CON), both ADO and AMP groups increased in carcass straight length (P < 0.05) and decreased in drip loss (P < 0.05), while AMP group tended to increase in redness value (P = 0.05) and decreased in free amino acid content in longissimus thoracis (LT) muscle (P < 0.05). Additionally, ADO or AMP supplementation increased the ADO or AMP content in serum, adipose tissue, and LT muscle (P < 0.05), as well as the protein level of adenosine 2A receptor (A2a) in adipose tissue (P < 0.05). Moreover, both ADO and AMP groups showed an increase in the expression of lipolysis genes (ATGL and HSL) in adipose tissue (P < 0.05). Overall, AMP supplementation could improve meat quality, and ADO and AMP supplementation regulate the lipid metabolism of finishing pigs.

本研究调查了添加腺苷 (ADO) 和腺苷 5'-单磷酸 (AMP) 对育肥猪生长性能、胴体特性、肉质和脂肪组织脂质代谢的影响。猪被分配到三个处理组：对照饮食、0.2% ADO 饮食或 0.2% AMP 饮食。与 CON 组（CON）相比，ADO 组和 AMP 组的胴体直长增加（P  < 0.05），滴水损失减少（P  < 0.05），而 AMP 组红度值有增加（ P  = 0.05）和减少的趋势胸最长肌 (LT) 肌肉中游离氨基酸含量的变化 ( P < 0.05)。此外，补充 ADO 或 AMP 可增加血清、脂肪组织和 LT 肌肉中的 ADO 或 AMP 含量（P  < 0.05），以及脂肪组织中腺苷 2A 受体 (A2a) 的蛋白水平（P  < 0.05）。此外，ADO 和 AMP 组均显示脂肪组织中脂肪分解基因（ ATGL和HSL ）的表达增加（P  < 0.05）。总的来说，添加AMP可以改善肉质，添加ADO和AMP可以调节肥育猪的脂质代谢。