The purpose of this work is to perform the conceptual design and process construction of $n$-propyl propionate synthesis by reactive distillation. Firstly, the reaction kinetic and thermodynamic models were summarized. The isobaric vapor-liquid equilibrium data of the binary systems 1-propanol (1) + $n$-propyl propionate (2) and propionic acid (1) + $n$-propyl propionate (2) were measured. The UNIQUAC model was used to describe the thermodynamic behavior of this system. Secondly, non-reactive residue curve maps and reactive residue curve maps analyses were used for conceptual design to obtain the preliminary configuration and operating conditions of the reactive distillation column. Finally, the sensitivity analysis was used to evaluate the preliminary process configuration and identify key operational variables.

这项工作的目的是进行概念设计和流程建设$n$-丙酸丙酯通过反应蒸馏合成。首先，总结了反应动力学和热力学模型。二元体系1-丙醇(1) + 的等压汽液平衡数据 $n$-丙酸丙酯 (2) 和丙酸 (1) + $n$-丙酸丙酯 (2) 被测量。UNIQUAC 模型用于描述该系统的热力学行为。其次，利用非反应残渣曲线图和反应残渣曲线图分析进行概念设计，得到反应精馏塔的初步配置和操作条件。最后，敏感性分析用于评估初步流程配置并确定关键操作变量。