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Associations between lower extremity muscle fat fraction and motor performance in myotonic dystrophy type 2: A pilot study
Muscle & Nerve ( IF 2.8 ) Pub Date : 2023-03-20 , DOI: 10.1002/mus.27821
Diana A Madrid 1 , Rebecca A Knapp 1, 2 , Delanie Lynch 1 , Paula Clemens 3 , Ashley A Weaver 1 , Araya Puwanant 4
Affiliation  

Although muscle structure measures from magnetic resonance imaging (MRI) have been used to assess disease severity in muscular dystrophies, little is known about how these measures are affected in myotonic dystrophy type 2 (DM2). We aim to characterize lower extremity muscle fat fraction (MFF) as a potential biomarker of disease severity, and evaluate its relationship with motor performance in DM2.

中文翻译:


强直性肌营养不良 2 型下肢肌肉脂肪分数与运动表现之间的关联:一项试点研究



尽管磁共振成像 (MRI) 的肌肉结构测量已用于评估肌营养不良症的疾病严重程度,但人们对这些测量在 2 型强直性肌营养不良 (DM2) 中如何受到影响知之甚少。我们的目标是将下肢肌肉脂肪分数 (MFF) 描述为疾病严重程度的潜在生物标志物,并评估其与 DM2 运动表现的关系。
更新日期:2023-03-20
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