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Lactobacillus murinus: A key factor in suppression of enterogenous Candida albicans infections in Compound Agrimony enteritis capsules-treated mice
Journal of Ethnopharmacology ( IF 4.8 ) Pub Date : 2023-03-22 , DOI: 10.1016/j.jep.2023.116361
Hui-Ting Chen 1 , Jia-Sheng Li 1 , Jun Li 2 , Li Li 1 , Zhi-Chang Xu 1 , Yi Zhang 1 , Rui-Rui Wang 1
Affiliation  

Compound Agrimony (FuFangXianHeCao, FFXHC) Enteritis Capsules is an ethnomedicine that is derived from Yi Nationality Herbal Medicine for enteritis treatment. We found that FFXHC reduced the mortality outcomes in enterogenic Candida albicans infected mice models and increased the abundance of Lactobacillus murinus in the intestines. Lactobacillus murinus exhibited comparable therapeutic effects to those of FFXHC in enterogenic Candida albicans infected mice. This study provides novel perspectives into the pharmacological mechanisms of FFXHC.

中文翻译:


鼠乳杆菌:抑制 Compound Agrimony 肠炎胶囊治疗小鼠肠源性白色念珠菌感染的关键因素



复方农业(FuFangXianHeCao,FFXHC)肠炎胶囊是一种源自彝族草药的民族药物,用于治疗肠炎。我们发现 FFXHC 降低了肠源性白色念珠菌感染小鼠模型的死亡率结果,并增加了肠道中鼠乳杆菌的丰度。鼠乳杆菌在肠源性白色念珠菌感染小鼠中表现出与 FFXHC 相当的治疗效果。本研究为 FFXHC 的药理机制提供了新的视角。
更新日期:2023-03-22
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