当前位置:
X-MOL 学术
›
J. Am. Chem. Soc.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Tris(bicyclo[1.1.1]pentyl)phosphine: An Exceptionally Small Tri-tert-alkylphosphine and Its Bis-Ligated Pd(0) Complex
Journal of the American Chemical Society ( IF 14.4 ) Pub Date : 2023-03-15 , DOI: 10.1021/jacs.3c00885 Griffin L Perry 1 , Nathan D Schley 1
Journal of the American Chemical Society ( IF 14.4 ) Pub Date : 2023-03-15 , DOI: 10.1021/jacs.3c00885 Griffin L Perry 1 , Nathan D Schley 1
Affiliation
Tris(bicyclo[1.1.1]pentyl)phosphine can be prepared by radical addition of PH3 to [1.1.1]propellane, giving the smallest tri-tert-alkylphosphine known. PBcp3 is substantially smaller than PCy3 and is comparable in electron-donating power to PEt3. It gives a bis-ligated Pd(0) complex Pd(PBcp3)2 that is exceptionally reactive toward alkyl halide oxidative addition and functions as a general ligand for palladium-catalyzed cross-coupling of sp3 electrophiles. Radical addition of [1.1.1]propellane to phenylphosphine gives the bis(bicyclo[1.1.1]pentyl)phosphine derivative PBcp2Ph, illustrating the generality of this approach to bicyclopentylphosphine synthesis.
中文翻译:
三(双环 [1.1.1] 戊基)膦:一种特别小的三叔烷基膦及其双连接 Pd(0) 络合物
三(双环[1.1.1]戊基)膦可以通过将PH 3自由基加成到[1.1.1]丙烷中来制备,得到已知最小的三叔烷基膦。PBcp 3显着小于PCy 3并且在给电子能力方面与PEt 3相当。它产生双连接的 Pd(0) 络合物 Pd(PBcp 3 ) 2,它对卤代烷氧化加成反应异常活跃,并作为钯催化的 sp 3亲电子试剂交叉偶联的通用配体。[1.1.1]propellane 与苯基膦的自由基加成得到双(双环[1.1.1]戊基)膦衍生物 PBcp 2Ph,说明了这种双环戊基膦合成方法的普遍性。
更新日期:2023-03-15
中文翻译:
三(双环 [1.1.1] 戊基)膦:一种特别小的三叔烷基膦及其双连接 Pd(0) 络合物
三(双环[1.1.1]戊基)膦可以通过将PH 3自由基加成到[1.1.1]丙烷中来制备,得到已知最小的三叔烷基膦。PBcp 3显着小于PCy 3并且在给电子能力方面与PEt 3相当。它产生双连接的 Pd(0) 络合物 Pd(PBcp 3 ) 2,它对卤代烷氧化加成反应异常活跃,并作为钯催化的 sp 3亲电子试剂交叉偶联的通用配体。[1.1.1]propellane 与苯基膦的自由基加成得到双(双环[1.1.1]戊基)膦衍生物 PBcp 2Ph,说明了这种双环戊基膦合成方法的普遍性。