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Sustainable electrochemical dearomatization for the synthesis of diverse 2, 3-functionalized indolines
Green Synthesis and Catalysis ( IF 8.2 ) Pub Date : 2022-10-22 , DOI: 10.1016/j.gresc.2022.10.009 Jun Chen , Rong Zhang , Caiyan Ma , Peng Zhang , Yonghong Zhang , Bin Wang , Fei Xue , Weiwei Jin , Yu Xia , Chenjiang Liu
中文翻译:
用于合成多种 2、3 功能化二氢吲哚的可持续电化学脱芳构化
更新日期:2022-10-22
Green Synthesis and Catalysis ( IF 8.2 ) Pub Date : 2022-10-22 , DOI: 10.1016/j.gresc.2022.10.009 Jun Chen , Rong Zhang , Caiyan Ma , Peng Zhang , Yonghong Zhang , Bin Wang , Fei Xue , Weiwei Jin , Yu Xia , Chenjiang Liu
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Herein, we achieved a green and efficient dearomatization for the synthesis of 2,3-functionalized polycyclic indolines in an electrochemical way. This avoiding of external oxidants and metals approach allowed various nucleophilic sources (Nu = anilines, TMSN3 and ROH) to perform the products, representing an environmentally benign means. Additionally, the continuous flow electrosynthesis and synthetic transformations also reveal the strong practicality of electrochemistry in organic synthesis.
中文翻译:

用于合成多种 2、3 功能化二氢吲哚的可持续电化学脱芳构化
在此,我们实现了以电化学方式合成 2,3-功能化多环二氢吲哚的绿色高效脱芳构化。这种避免外部氧化剂和金属的方法允许各种亲核源(Nu = 苯胺、TMSN 3和 ROH)来执行产品,代表一种环境友好的方式。此外,连续流动电合成和合成转化也揭示了电化学在有机合成中的强大实用性。