A new method for the preparation of 5-trifluoromethyl-5-cyclopropylpyrazoline derivatives via cesium hydroxide mediated condensation reaction of ꞵ-trifluoromethyl-ꞵ-cyclopropyl-substituted unsaturated ketones with hydrazines was reported. The approach featuring mild reaction conditions, broad substrates scope and good functional group tolerance, provided a strategy to synthesize new functionalized pyrazolines bearing both trifluoromethyl and cyclopropyl groups.

中文翻译：

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5-三氟甲基-5-环丙基取代吡唑啉的简便合成

报道了一种通过氢氧化铯介导的 ꞵ-三氟甲基-ꞵ-环丙基取代的不饱和酮与肼的缩合反应制备 5-三氟甲基-5-环丙基吡唑啉衍生物的新方法。该方法具有温和的反应条件、广泛的底物范围和良好的官能团耐受性，为合成同时带有三氟甲基和环丙基的新型功能化吡唑啉提供了一种策略。