Selenium (Se) and metal-doped carbon dots (CDs) based nanoenzymes have bright prospects as antioxidants; however, the high cost of Se and potential biotoxicity of metal elements hinder their widespread application. In this work, inspired by Chinese herbs with anti-inflammatory properties, SB-HHD-CDs were prepared using Scutellaria barbata (SB) and Herba Hedyotis diffusae (HHD) as precursors through a hydrothermal method. The SB-HHD-CDs with excellent thermal and pH stability could rapidly scavenge multiple reactive oxygen and nitrogen species (RONS), such as superoxide anion, hydroxyl radicals, 1,1-diphenyl-2-picryl-hydrazyl radicals and nitric oxide radicals, at low concentrations. To demonstrate, the as-prepared SB-HHD-CDs were used as cost-effective additives and integrated into a cigarette filter system to effectively remove more than 80% of RONS from cigarette burning. Our work provides a new strategy for the synthesis of novel Se- and metal-free doped CDs-based nanoenzymes with powerful antioxidant capacity.

中文翻译：

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碳点作为潜在的抗氧化剂，用于清除多活性氧和氮物种


硒（Se）和金属掺杂碳点（CD）基纳米酶作为抗氧化剂具有广阔的前景；然而，硒的高成本和金属元素潜在的生物毒性阻碍了其广泛应用。在这项工作中，受具有抗炎特性的中草药的启发，以半枝莲（SB）和白花蛇舌草（HHD）为前体，通过水热法制备了SB-HHD-CD。 SB-HHD-CD具有优异的热稳定性和pH稳定性，可以快速清除多种活性氧和氮物种（RONS），如超氧阴离子、羟基自由基、1,1-二苯基-2-苦基肼自由基和一氧化氮自由基，在低浓度下。为了证明这一点，所制备的 SB-HHD-CD 被用作具有成本效益的添加剂，并集成到卷烟过滤嘴系统中，可有效去除卷烟燃烧中 80% 以上的 RONS。我们的工作为合成具有强大抗氧化能力的新型无硒和无金属掺杂环糊精纳米酶提供了新策略。