Photosensitized Vicinal Sulfonylamination of Alkenes with Oxime Ester and DABCO·(SO2)2,Organic Letters

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Photosensitized Vicinal Sulfonylamination of Alkenes with Oxime Ester and DABCO·(SO2)2
Organic Letters ( IF 4.9 ) Pub Date : 2023-03-08 , DOI: 10.1021/acs.orglett.3c00559
Chu-Ping Yuan ₁ , Yu Zheng ₁ , Zhen-Zhen Xie ₁ , Ke-Yi Deng ₁ , Hong-Bin Chen _{1,

2} , Hao-Yue Xiang ₁ , Kai Chen ₁ , Hua Yang ₁

Affiliation

A metal-free photosensitized three-component reaction of oxime esters, alkenes, and DABCO·(SO₂)₂ was developed. This protocol could accommodate a wide substrate scope, including activated and unactivated alkenes and aryl and aliphatic carboxylic acid oxime esters, delivering a broad range of β-amino sulfones in moderate to high yields. The insertion of SO₂ as a linker moiety allows the manipulation of the functionality in the reaction process, expanding the utility of oxime esters as bifunctional reagents.

中文翻译：

烯烃与肟酯和 DABCO 的光敏邻位磺酰化反应·(SO2)2

开发了肟酯、烯烃和 DABCO·(SO ₂ ) ₂的无金属光敏三组分反应。该协议可以适应广泛的底物范围，包括活化和未活化的烯烃以及芳基和脂肪族羧酸肟酯，以中高产率提供广泛的 β-氨基砜。_{SO 2}作为连接部分的插入允许在反应过程中操纵功能，扩大肟酯作为双功能试剂的效用。

更新日期：2023-03-08

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