Acrylamide exposure through environment pollution and diet is very common in daily life. With the deepening of the study on the toxicity of acrylamide, it has attracted widespread attention for the effects of acrylamide on multiple organs through affecting a variety of programmed cell death. Multiple studies have shown that acrylamide could exert its toxic effect by inducing programmed cell death, but its specific molecular mechanism is still unclear. In this review, the research on the main forms of programmed cell death (apoptosis, autophagy, and programmed necrosis) induced by acrylamide and their possible mechanisms are reviewed. This review may provide basic data for further research of acrylamide and prevention of its toxicity.

中文翻译：

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丙烯酰胺诱导细胞程序性死亡的研究进展

通过环境污染和饮食接触丙烯酰胺在日常生活中非常普遍。随着对丙烯酰胺毒性研究的深入，丙烯酰胺通过影响多种程序性细胞死亡对多器官的影响引起了广泛关注。多项研究表明，丙烯酰胺可通过诱导细胞程序性死亡发挥其毒性作用，但其具体分子机制尚不清楚。本文就丙烯酰胺诱导细胞程序性死亡的主要形式（细胞凋亡、自噬和程序性坏死）及其可能机制的研究作一综述。该综述可为进一步研究丙烯酰胺及其毒性防治提供基础数据。