当前位置：
X-MOL 学术
›
Chem. Commun.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Silver cluster-assembled materials for label-free DNA detection
Chemical Communications ( IF 4.3 ) Pub Date : 2023-02-27 , DOI: 10.1039/d2cc06933d Saikat Das 1 , Taishu Sekine 1 , Haruna Mabuchi 1 , Sakiat Hossain 1 , Subhabrata Das 2 , Shun Aoki 3 , Shuntaro Takahashi 2 , Yuichi Negishi 1
Chemical Communications ( IF 4.3 ) Pub Date : 2023-02-27 , DOI: 10.1039/d2cc06933d Saikat Das 1 , Taishu Sekine 1 , Haruna Mabuchi 1 , Sakiat Hossain 1 , Subhabrata Das 2 , Shun Aoki 3 , Shuntaro Takahashi 2 , Yuichi Negishi 1
Affiliation
|
Herein, we report two newly synthesized silver cluster-assembled materials (SCAMs), [Ag14(StBu)10(CF3COO)4(bpa)2]n (bpa = 1,2-bis(4-pyridyl)acetylene) and [Ag12(StBu)6(CF3COO)6(bpeb)3]n (bpeb = 1,4-bis(pyridin-4-ylethynyl)benzene) composed of Ag14 and Ag12 chalcogenolate cluster cores, respectively, bridged by acetylenic bispyridine linkers. The linker structures and electrostatic interaction between positively charged SCAMs and negatively charged DNA confer the SCAMs with the ability to suppress the high background fluorescence of single-stranded (ss) DNA probes with SYBR Green I nucleic acid stain, leading to high signal-to-noise ratio for label-free target DNA detection.
中文翻译：
用于无标记 DNA 检测的银簇组装材料
在此，我们报告了两种新合成的银簇组装材料 (SCAM)，[Ag 14 (S t Bu) 10 (CF 3 COO) 4 (bpa) 2 ] n (bpa = 1,2-bis(4-pyridyl)乙炔)和[Ag 12 (S t Bu) 6 (CF 3 COO) 6 (bpeb) 3 ] n (bpeb = 1,4-bis(pyridin-4-ylethynyl)benzene) 由 Ag 14和 Ag 12组成硫属元素化物簇核分别由炔属双吡啶接头桥接。带正电荷的 SCAM 和带负电荷的 DNA 之间的接头结构和静电相互作用赋予 SCAM 抑制单链 (ss) DNA 探针与 SYBR Green I 核酸染色的高背景荧光的能力，从而导致高信号转无标记目标 DNA 检测的噪声比。
更新日期：2023-02-27
中文翻译：
用于无标记 DNA 检测的银簇组装材料
在此，我们报告了两种新合成的银簇组装材料 (SCAM)，[Ag 14 (S t Bu) 10 (CF 3 COO) 4 (bpa) 2 ] n (bpa = 1,2-bis(4-pyridyl)乙炔)和[Ag 12 (S t Bu) 6 (CF 3 COO) 6 (bpeb) 3 ] n (bpeb = 1,4-bis(pyridin-4-ylethynyl)benzene) 由 Ag 14和 Ag 12组成硫属元素化物簇核分别由炔属双吡啶接头桥接。带正电荷的 SCAM 和带负电荷的 DNA 之间的接头结构和静电相互作用赋予 SCAM 抑制单链 (ss) DNA 探针与 SYBR Green I 核酸染色的高背景荧光的能力，从而导致高信号转无标记目标 DNA 检测的噪声比。
京公网安备 11010802027423号