Purpose

This study aimed to explore the value of pre-/post-contrast-enhanced T1 mapping and readout segmentation of long variable echo-train diffusion-weighted imaging (RESOLVE-DWI) for the differential diagnosis of parotid gland tumors.

Methods

A total of 128 patients with histopathologically confirmed parotid gland tumors [86 benign tumors (BTs) and 42 malignant tumors (MTs)] were retrospectively recruited. BTs were further divided into pleomorphic adenomas (PAs, n = 57) and Warthin’s tumors (WTs, n = 15). MRI examinations were performed before and after contrast injection to measure the longitudinal relaxation time (T1) value (T1p and T1e, respectively) and the apparent diffusion coefficient (ADC) value of the parotid gland tumors. The reduction in T1 (T1d) values and the percentage of T1 reduction (T1d%) were calculated.

Results

The T1d and ADC values of the BTs were considerably higher than those of the MTs (all P <.05). The area under the curve (AUC) of the T1d and ADC values for differentiating between BTs and MTs of the parotid was 0.618 and 0.804, respectively (all P <.05). The AUC of the T1p, T1d, T1d%, and ADC values for differentiating between PAs and WTs was 0.926, 0.945, 0.925, and 0.996, respectively (all P >.05). The ADC and T1d% + ADC values performed better in differentiating between PAs and MTs than the T1p, T1d, and T1d% (AUC values: 0.902, 0.909, 0.660, 0.726, and 0.736, respectively). The T1p, T1d, T1d%, and T1d% + T1p values all had high diagnosis efficacy in differentiating WTs from MTs (AUC values: 0.865, 0.890, 0.852, and 0.897, respectively, all P >.05).

Conclusion

T1 mapping and RESOLVE-DWI can be used to differentiate parotid gland tumors quantitatively and can be complementary to each other.

中文翻译：

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长可变回波序列扩散加权成像前后对比增强 T1 映射和读出分割在鉴别腮腺肿瘤中的价值

目的

本研究旨在探讨长可变回波序列扩散加权成像（RESOLVE-DWI）前后对比增强 T1 映射和读出分割对腮腺肿瘤鉴别诊断的价值。

方法

回顾性招募了总共 128 名经组织病理学证实的腮腺肿瘤患者 [86 名良性肿瘤 (BT) 和 42 名恶性肿瘤 (MT)]。BT 进一步分为多形性腺瘤 (PAs，n  = 57) 和 Warthin 肿瘤 (WTs，n  = 15)。在造影剂注射前后进行MRI检查，测量腮腺肿瘤的纵向弛豫时间（T1）值（分别为T1p和T1e）和表观扩散系数（ADC）值。计算 T1 (T1d) 值的减少和 T1 减少的百分比 (T1d%)。

结果

BT 的 T1d 和 ADC 值明显高于 MT（所有P  <.05）。用于区分腮腺 BT 和 MT 的 T1d 和 ADC 值的曲线下面积 (AUC) 分别为 0.618 和 0.804（所有P  <.05）。用于区分 PA 和 WT 的 T1p、T1d、T1d% 和 ADC 值的 AUC 分别为 0.926、0.945、0.925 和 0.996（所有P  >.05）。ADC 和 T1d% + ADC 值在区分 PA 和 MT 方面比 T1p、T1d 和 T1d% 表现更好（AUC 值：分别为 0.902、0.909、0.660、0.726 和 0.736）。T1p、T1d、T1d% 和 T1d% + T1p 值在区分 WT 和 MT 方面均具有很高的诊断效能（AUC 值：分别为 0.865、0.890、0.852 和 0.897，所有P >.05).

结论

T1 mapping和RESOLVE-DWI可用于腮腺肿瘤的定量鉴别，可以互补。