The efficiency of heterogeneous electro-Fenton technology on the degradation of recalcitrant organic pollutants in wastewater is glaringly obvious. This green technology can be effectively harnessed for addressing ever-increasing water-related challenges. Due to its outstanding performance, eco-friendliness, easy automation, and operability over a wide range of pH, it has garnered significant attention from different wastewater treatment research communities. This review paper briefly discusses the principal mechanism of the electro-Fenton process, the crucial properties of a highly efficient heterogeneous catalyst, the heterogeneous electro-Fenton system enabled with Fe-functionalized cathodic materials, and its essential operating parameters. Moreover, the authors comprehensively explored the major challenges that prevent the commercialization of the electro-Fenton process and propose future research pathways to countervail those disconcerting challenges. Synthesizing heterogeneous catalysts by application of advanced materials for maximizing their reusability and stability, the full realization of H₂O₂ activation mechanism, conduction of life-cycle assessment to explore environmental footprints and potential adverse effects of side-products, scale-up from lab-scale to industrial scale, and better reactor design, fabrication of electrodes with state-of-the-art technologies, using the electro-Fenton process for treatment of biological contaminants, application of different effective cells in the electro-Fenton process, hybridization of the electro-Fenton with other wastewater treatments technologies and full-scale analysis of economic costs are key recommendations which deserve considerable scholarly attention. Finally, it concludes that by implementing all the abovementioned gaps, the commercialization of electro-Fenton technology would be a realistic goal.

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