Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro-N-phenylacetamide,Drug and Chemical Toxicology

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Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro-N-phenylacetamide
Drug and Chemical Toxicology ( IF 2.1 ) Pub Date : 2023-02-20 , DOI: 10.1080/01480545.2022.2158849
Elba Dos Santos Ferreira ₁ , Laísa Vilar Cordeiro ₁ , Daniele de Figuerêdo Silva ₁ , Hermes Diniz Neto ₁ , Aleson Pereira de Sousa ₂ , Helivaldo Diógenes da Silva Souza ₃ , Petrônio Filgueiras de Athayde-Filho ₃ , Felipe Queiroga Sarmento Guerra ₄ , José Maria Barbosa-Filho ₁ , Abrahão Alves de Oliveira Filho ₅ , Edeltrudes de Oliveira Lima ₁ , Ricardo Dias de Castro ₁

Affiliation

Aspergillus niger causes infections such as otitis and pulmonary aspergillosis in immunocompromised individuals. Treatment involves voriconazole or amphotericin B, and due to the increase in fungal...

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