硫氰酸盐 (SCN) 是氰化物解毒过程中的一种有害副产品。即使数量很少,SCN 也会对健康产生负面影响。尽管 SCN 分析有多种方法,但几乎从未尝试过有效的电化学程序。在这里,作者报告了利用掺入 MXene (PEDOT/MXene) 改性丝网印刷电极 (SPE) 的聚 (3, 4-亚乙基二氧噻吩) 开发用于 SCN 的高选择性和灵敏电化学传感器。拉曼、X 射线光电子 (XPS) 和 X 射线衍射 (XRD) 分析支持 PEDOT 在 MXene 表面上的有效整合。此外,使用扫描电子显微镜 (SEM) 来证明 MXene 和 PEDOT/MXene 混合膜的形成。为了特异性检测磷酸盐缓冲介质 (pH 7.4) 中的 SCN,PEDOT/MXene杂化薄膜通过电化学沉积方法生长在SPE表面。在优化条件下,基于 PEDOT/MXene/SPE 的传感器对 SCN 的线性响应范围为 10 至 100 μM 和 0.1 μM 至 1000 μM,差分脉冲伏安法的最低检测限 (LOD) 为 1.44 μM 和 0.0325 μM (DPV)和安培法,分别。为了准确检测 SCN,我们新创建的 PEDOT/MXene 混合薄膜包被 SPE 展示了出色的灵敏度、选择性和可重复性。最终,这种新型传感器可用于精确检测环境和生物样品中的 SCN。1 μM 至 1000 μM,差分脉冲伏安法 (DPV) 和安培法的最低检测限 (LOD) 分别为 1.44 μM 和 0.0325 μM。为了准确检测 SCN,我们新创建的 PEDOT/MXene 混合薄膜包被 SPE 展示了出色的灵敏度、选择性和可重复性。最终,这种新型传感器可用于精确检测环境和生物样品中的 SCN。1 μM 至 1000 μM,差分脉冲伏安法 (DPV) 和安培法的最低检测限 (LOD) 分别为 1.44 μM 和 0.0325 μM。为了准确检测 SCN,我们新创建的 PEDOT/MXene 混合薄膜包被 SPE 展示了出色的灵敏度、选择性和可重复性。最终,这种新型传感器可用于精确检测环境和生物样品中的 SCN。
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Amperometric determination of salivary thiocyanate using electrochemically fabricated poly (3, 4-ethylenedioxythiophene)/MXene hybrid film
Thiocyanate (SCN) is a hazardous byproduct of the detoxification of cyanide. Even in minute quantity, the SCN has a negative impact on health. Although there are several ways for SCN analysis, an efficient electrochemical procedure has hardly ever been attempted. Here, the author reports the development of a highly selective and sensitive electrochemical sensor for SCN utilizing Poly (3, 4-Ethylenedioxythiophene) incorporated MXene (PEDOT/MXene) modified screen-printed electrode (SPE). The Raman, X-ray photoelectron (XPS), and X-ray diffraction (XRD) analyses support the effective integration of PEDOT on the MXene surface. Further, scanning electron microscopy (SEM) is employed to demonstrate the formation of MXene and PEDOT/MXene hybrid film. In order to specifically detect SCN in phosphate buffer media (pH 7.4), the PEDOT/MXene hybrid film is grown on the SPE surface via the electrochemical deposition method. Under the optimized condition, the PEDOT/MXene/SPE-based sensor provides a linear response against SCN from 10 to 100 µM and 0.1 μM to 1000 μM with the lowest limit of detections (LOD) of 1.44 μM and 0.0325 μM by differential pulse voltammetry (DPV) and amperometry, respectively. For accurate detection of SCN, our newly created PEDOT/MXene hybrid film-coated SPE demonstrates excellent sensitivity, selectivity, and repeatability. Ultimately, this novel sensor can be used to detect SCN precisely in environmental and biological samples.