Polyhedra have long appeared throughout art and design for their aesthetic topological features and, more recently, have found versatile roles in supramolecular chemistry and organized materials. Non-regular convex tetrahedra with positive augmentations of a regular tetrahedron, for example an isohedral triakis tetrahedron, have rarely been explored in synthetic chemistry. Herein, we report the synthesis of a giant triakis tetrahedron through multi-component self-assembly from four umbrella-shaped hexa-armed organic terpyridine ligands and six pre-organized cadmium-containing building blocks. Hexafunctionalized tribenzotriquinacene cavitands serve as the scaffold for the formation of the triakis tetrahedron. The convex vertices derived from rhomboid panels form four trigonal-pyramidal cages based on regular tetrahedral faces. Characterization with multiple types of nuclear magnetic resonance spectroscopy, mass spectrometry, atomic resolution microscopy, and X-ray scattering provide crucial structural information on the triakis tetrahedron. The triakis tetrahedron is applied in the photo-driven degradation of a sulfur mustard mimic. The principles developed herein enhance the possible topological diversity of supramolecular coordination polyhedra.

多面体因其美观的拓扑特征而长期出现在艺术和设计中，并且最近在超分子化学和有组织的材料中发现了多种用途。在合成化学中很少探索具有正四面体正增强的非常规凸四面体，例如等面体三角四面体。在此，我们报道了通过由四个伞形六臂有机三联吡啶配体和六个预先组织的含镉结构单元进行多组分自组装，合成了一个巨大的 triakis 四面体。六官能化三苯并三喹并烯空穴作为形成三四面体的支架。源自菱形面板的凸顶点形成四个基于正四面体面的三角锥形笼。多种类型的核磁共振波谱、质谱、原子分辨率显微镜和 X 射线散射的表征提供了关于 triakis 四面体的关键结构信息。triakis 四面体应用于硫芥模拟物的光驱动降解。本文开发的原理增强了超分子配位多面体的可能拓扑多样性。