当前位置：
X-MOL 学术
›
Chem. Commun.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Enantioselective dearomatization reactions of heteroarenes by anion-binding organocatalysis
Chemical Communications ( IF 4.3 ) Pub Date : 2023-02-15 , DOI: 10.1039/d2cc07101k Martin Aleksiev 1 , Olga García Mancheño 1
Chemical Communications ( IF 4.3 ) Pub Date : 2023-02-15 , DOI: 10.1039/d2cc07101k Martin Aleksiev 1 , Olga García Mancheño 1
Affiliation
|
Catalytic asymmetric dearomatization of heteroaromatic compounds has received considerable attention in the last few years, since it allows for a fast expansion of the chemical space by converting relatively simple, flat molecules into complex, three dimensional structures with added value. Among different approaches, remarkable progress has been recently achieved by the development of organocatalytic dearomatization methods. In particular, the anion-binding catalysis technology has emerged as a potent alternative to metal catalysis, which together with the design of novel, tunable anion-receptor motifs, has provided new entries for the enantioselective dearomatization of heteroarenes through a chiral contact ion pair formation by activation of the electrophilic reaction partner. In this feature, we provide an overview of the different methodologies and advances in anion-binding catalyzed dearomatization reactions of different heteroarenes.
中文翻译：
阴离子结合有机催化杂芳烃的对映选择性脱芳构化反应
杂芳族化合物的催化不对称脱芳构化在过去几年受到了相当大的关注，因为它通过将相对简单的扁平分子转化为具有附加值的复杂三维结构来快速扩展化学空间。在不同的方法中，有机催化脱芳构化方法的发展最近取得了显着进展。特别是，阴离子结合催化技术已成为金属催化的有力替代品，它与新型可调阴离子受体基序的设计一起，为通过手性接触离子对形成杂芳烃的对映选择性脱芳构化提供了新的入口通过激活亲电反应伙伴。在这个功能中，
更新日期：2023-02-15
中文翻译：
阴离子结合有机催化杂芳烃的对映选择性脱芳构化反应
杂芳族化合物的催化不对称脱芳构化在过去几年受到了相当大的关注，因为它通过将相对简单的扁平分子转化为具有附加值的复杂三维结构来快速扩展化学空间。在不同的方法中，有机催化脱芳构化方法的发展最近取得了显着进展。特别是，阴离子结合催化技术已成为金属催化的有力替代品，它与新型可调阴离子受体基序的设计一起，为通过手性接触离子对形成杂芳烃的对映选择性脱芳构化提供了新的入口通过激活亲电反应伙伴。在这个功能中，
京公网安备 11010802027423号