In this work, wet oxidation and catalytic wet oxidation of pharmaceutical sludge using homogeneous and heterogeneous catalysts were investigated. The results indicate that wet oxidation is a promising method for the highly efficient degradation of pharmaceutical sludge. Under optimal conditions, the highest removal efficiencies of volatile suspended solids (VSS) 86.8% and chemical oxygen demand (COD) 62.5% were achieved at 260 °C for 60 min with an initial oxygen pressure of 1.0 MPa. NaOH exhibited excellent acceleration performance on the VSS removal. The highest VSS removal efficiency of 95.2% was obtained at 260 °C for 60 min with an initial oxygen pressure of 1.0 MPa and 10 g·L⁻¹ of NaOH. By using a Cu–Ce/γ-Al₂O₃ catalyst, the highest removal rates of VSS 87.3% and COD 72.6% were achieved at 260 °C for 60 min with an initial oxygen pressure of 1.0 MPa and 10 g·L⁻¹ of catalyst. The wet oxidation reaction can be maintained itself owing to the exothermic heat. The produced low-molecular-weight carboxylic acids have potential commercial utilization as organic carbon sources in the biological wastewater treatment processes. The inorganic residues can be utilized for the building materials production. These results implied that the catalytic wet oxidation is a promising method for the volume reduction and resource utilization of pharmaceutical sludge.

在这项工作中，研究了使用均相和非均相催化剂对制药污泥进行湿法氧化和催化湿法氧化。结果表明，湿法氧化是高效降解制药污泥的一种很有前途的方法。在最佳条件下，挥发性悬浮固体 (VSS) 的最高去除效率为 86.8%，化学需氧量 (COD) 为 62.5%，在 260 °C 下持续 60 分钟，初始氧气压力为 1.0 MPa。NaOH 表现出优异的 VSS 去除加速性能。95.2% 的最高 VSS 去除效率在 260 °C 下获得 60 分钟，初始氧气压力为 1.0 MPa 和 10 g·L ^-1 NaOH。通过使用 Cu–Ce/γ-Al ₂ O ₃催化剂，VSS 87.3% 和 COD 72.6% 的最高去除率是在 260 °C 下保持 60 分钟，初始氧气压力为 1.0 MPa 和 10 g·L -1^催化剂。由于放热，湿式氧化反应可以自行维持。所产生的低分子量羧酸作为生物废水处理过程中的有机碳源具有潜在的商业用途。无机残渣可用于建材生产。这些结果表明，催化湿法氧化是制药污泥减容和资源化利用的一种有前途的方法。