Covalent organic frameworks (COFs) membranes have exhibited great applications in wastewater treatment due to their highly ordered porous architecture. Currently, numerous studies have focused on the hexagonal-structured COFs synthesized with linear C2 and C3 precursor. However, the C2 monomer is limited-variety and high-cost. Herein, a novel clover-like structure COFs membrane is successfully fabricated for the first time. Meta-position monomer m-phenylenediamine (MPD) and 1,3,5-triformylbenzene (TFB) are used to synthesize the clover-like COFs membrane by interfacial polymerization (IP) method on the nylon substrate directly. The optimized MPD-TFB/Nylon membrane shows excellent water permeance of 94.4 L m⁻² h⁻¹ bar⁻¹, which is higher than hexagonal-structured COFs membrane, in Congo red (CR) and NaCl mixed solution The rejections are 98.6% for CR and 2.9% for NaCl. This work opens a novel route for designing the COFs membrane with clover-like channels, manifesting the usage of linear C2 monomers is unnecessary. Besides, it has been found that the unique clover-like structure can improve the water molecular transport path under the same dye molecules deposition situation compared with hexagonal structure COFs membrane.

共价有机骨架 (COF) 膜由于其高度有序的多孔结构而在废水处理中展现出巨大的应用。目前，许多研究都集中在用线性 C2 和 C3 前驱体合成的六方结构 COFs。然而，C2单体品种有限且成本高。在此，首次成功制备了一种新型的类三叶草结构COFs膜。间位单体间苯二胺 (MPD) 和 1,3,5-三甲酰苯 (TFB) 通过界面聚合 (IP) 法直接在尼龙基底上合成三叶草状 COFs 膜。^{优化的 MPD-TFB/尼龙膜显示出 94.4 L m −2}  h ⁻¹ bar ⁻¹的出色透水性，高于六方结构的COFs膜，在刚果红（CR）和NaCl混合溶液中，CR的截留率为98.6%，NaCl的截留率为2.9%。这项工作为设计具有三叶草状通道的 COFs 膜开辟了一条新途径，表明不需要使用线性 C2 单体。此外，已经发现与六方结构COFs膜相比，独特的三叶草状结构可以在相同染料分子沉积情况下改善水分子传输路径。