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Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
Nano-Micro Letters ( IF 31.6 ) Pub Date : 2023-02-08 , DOI: 10.1007/s40820-023-01018-4
Qingfei Zhang 1, 2 , Gaizhen Kuang 1, 2 , Wenzhao Li 1, 2 , Jinglin Wang 1 , Haozhen Ren 1 , Yuanjin Zhao 1, 3, 4
Affiliation  

  • Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs.

  • Recent advances in stimuli-responsive GDNCs for cancer therapy are classified, summarized, and exhibited by representative examples.

  • The potential challenges and prospects of stimuli-responsive GDNCs toward clinical translation are outlined and the future research directions are outlooked.



中文翻译:


用于癌症治疗的刺激响应基因递送纳米载体



  • 刺激响应基因递送纳米载体 (GDNCs) 因其有效保护、延长血液循环、选择性和靶向递送以及核酸药物的控释而在基因治疗领域具有巨大的潜力。


  • 对用于癌症治疗的刺激反应 GDNC 的最新进展进行了分类、总结,并通过代表性实例进行了展示。


  • 概述了刺激响应 GDNC 对临床转化的潜在挑战和前景,并展望了未来的研究方向。

更新日期:2023-02-08
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