Two novel dicyclic C-geranylated flavanones, fortunones D (1) and E (2), were isolated from the fresh mature fruits of Paulownia fortunei (Seem.) Hemsl. Their structures were elucidated by the extensive spectroscopic data analyses (UV, HRMS NMR, and CD). Each of these two isolated compounds possessed an unusual dicyclic geranyl group. Compounds 1 was more sensitive to human lung cancer cell A549 and exhibited potential anti-tumor effect (IC₅₀ = 9.72 μM).

中文翻译：

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从泡桐中分离出的两个新的双环 C-香叶基黄烷酮及其细胞毒性

从Paulownia fortunei (Seem.) Hemsl的新鲜成熟果实中分离出两种新型双环C-香叶基化黄烷酮，fortunones D ( 1 ) 和 E ( 2 )。它们的结构通过广泛的光谱数据分析（UV、HRMS NMR 和 CD）得到阐明。这两种分离的化合物中的每一种都具有不寻常的双环香叶基。化合物1对人肺癌细胞 A549 更敏感，并表现出潜在的抗肿瘤作用 (IC ₅₀ = 9.72  μ M)。