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通过编辑大肠杆菌中的稀有精氨酸密码子阐明了密码子选择的紧急规则[遗传]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2016-09-20 08:46:01 , DOI: 10.1073/pnas.1605856113 Michael G. Napolitano 1, 2, 3 , Matthieu Landon 1, 2, 4, 5 , Christopher J. Gregg 1, 2 , Marc J. Lajoie 1, 2, 6 , Lakshmi Govindarajan 7 , Joshua A. Mosberg 1, 2, 6 , Gleb Kuznetsov 1, 2, 8 , Daniel B. Goodman 1, 2, 9 , Oscar Vargas-Rodriguez 10 , Farren J. Isaacs 11 , Dieter Söll 10, 12 , George M. Church 1, 2
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2016-09-20 08:46:01 , DOI: 10.1073/pnas.1605856113 Michael G. Napolitano 1, 2, 3 , Matthieu Landon 1, 2, 4, 5 , Christopher J. Gregg 1, 2 , Marc J. Lajoie 1, 2, 6 , Lakshmi Govindarajan 7 , Joshua A. Mosberg 1, 2, 6 , Gleb Kuznetsov 1, 2, 8 , Daniel B. Goodman 1, 2, 9 , Oscar Vargas-Rodriguez 10 , Farren J. Isaacs 11 , Dieter Söll 10, 12 , George M. Church 1, 2
Affiliation
遗传密码的简并性允许核酸编码氨基酸同一性以及用于基因调节和基因组维持的非编码信息。稀有的精氨酸密码子AGA和AGG(AGR)代表了密码子选择的案例研究,其中AGR编码的重要转录和翻译特性不同于...
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更新日期:2016-09-22
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