This review described the preparation of 2-chloroquinoline-3-carbaldehyde derivatives through Vilsmeier-Haack formylation of N-arylacetamides and their use as a key intermediate for the preparation of 2-aminoquinoline-3-carbaldehydes. The synthesis of the 2-aminoquinolines can be done through the following chemical reactions: Claisen-Schmidt condensation, 1, 3-dipolar cycloaddition, one-pot multicomponent reactions (MCRs), and reductive amination.

中文翻译：

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2-氨基喹啉的化学：合成、反应性和生物活性

本综述描述了通过 N-芳基乙酰胺的 Vilsmeier-Haack 甲酰化制备 2-氯喹啉-3-甲醛衍生物及其作为制备 2-氨基喹啉-3-甲醛的关键中间体的用途。2-氨基喹啉的合成可通过以下化学反应完成：Claisen-Schmidt 缩合、1, 3-偶极环加成、一锅多组分反应 (MCR) 和还原胺化。